Little Busters! The 4-koma(2006)

Little Busters!' story revolves around the main protagonist Riki Naoe, a young male high school student. When Riki was a child, his parents died, leaving him hopeless and depressed. What saved him was a group of his friends who referred to themselves as the Little Busters; they took Riki out and played together with him during his time of need. He really enjoyed playing with them, and his grief gradually faded away. When the story begins, they are in their second year of the high school they attend. They still hang out together, and enjoy their school life. (c) Wikipedia